How do these Regenerative biomaterials work?
Updated: Jan 3, 2021
Prof Paul Lee - MSK Regeneration Blog on MSK Doctors
Depending on the nature of the injury and the nature of what we would like these bioactive materials to do, the way they work is very different.
Sometimes these materials can provide a scaffold or a foundation for our body to heal and for the cells to grow. Sometimes these products are to produce and promote the growth factors around the injured site. Sometimes these biological products deliberately try to induce an inflammatory response within the host's body.
The treatment of using a platelet-rich plasma is very complex. For example, there is platelet-rich plasma, platelet poor plasma, leukocyte-rich plasma, leukocyte-poor plasma, leukocyte-rich platelet poor plasma, leukocyte-rich, platelet-rich plasma. These are just the tip of the iceberg, as there are different components of the cells that we can activate and different components of the blood itself we can isolate to use for treatment.
Ultimately, the biomaterial that we produce is to help the body to repair, augment and regenerate. It is a big step forward in modern medicine and we are trying to guide and allow our body to heal ourselves.
The Regeneration Man
MBBch, MFSEM (UK), MSc (Sports Med), PhD (Med Engine), FEBOT, FRCS (Tr & Orth)
Consultant Sports and Arthroplasty Surgeon
MSK and Regeneration Medicine Doctor
Visiting Professor of Sports Medicine
I.C.R.S. teaching centre of excellence
Regional advisor Royal College of Surgeon Ed
Passionate about biology, engineering, computers and medicine.
Sports Muscle Injuries and Actovegin: Basics, Concepts and Future of Actovegin by Paul Y. F. Lee (2016-02-22)